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1.
Neutralizing antibodies against SARS-CoV-2 variants following mRNA booster vaccination in adults older than 65 years.
Durier, Christine; Ninove, Laetitia; Lefebvre, Maeva; Radenne, Anne; Desaint, Corinne; Ropers, Jacques; Bauer, Rebecca; Lebbah, Said; Carette, Diane; Lachatre, Marie; Lecompte, Anne-Sophie; Deplanque, Dominique; Botelho-Nevers, Elisabeth; Conrad, Anne; Dussol, Bertrand; Maakaroun-Vermesse, Zoha; Melica, Giovanna; Nicolas, Jean-François; Verdon, Renaud; Kiladjian, Jacques; Loubet, Paul; Schmidt-Mutter, Catherine; Dualé, Christian; Ansart, Séverine; Priet, Stéphane; Levier, Axel; Molino, Diana; Vieillard, Louis-Victorien; Parfait, Béatrice; Lelièvre, Jean-Daniel; Tartour, Eric; de Lamballerie, Xavier; Launay, Odile.
Sci Rep ; 12(1): 20373, 2022 Nov 27.
Article in English | MEDLINE | ID: covidwho-2133622

ABSTRACT

Immune response induced by COVID-19 vaccine booster against delta and omicron variants was assessed in 65 adults (65-84 years old) early aftesr a first booster dose. An increase in SARS-CoV-2 neutralizing antibodies was shown in individuals not previously infected without evidence of an age-related effect, with lower increase in those infected before a single dose of primary vaccination. Of note, humoral response was observed only starting from the 5th day after the boost.


Subject(s)
COVID-19 , Viral Vaccines , Humans , Aged , Aged, 80 and over , Antibodies, Neutralizing , SARS-CoV-2/genetics , Neutralization Tests , Antibodies, Viral , RNA, Messenger , COVID-19/prevention & control , Vaccination
2.
A comparison of Sars-Cov-2 vaccine platforms: the CoviCompare project.
Molino, Diana; Durier, Christine; Radenne, Anne; Desaint, Corinne; Ropers, Jacques; Courcier, Soizic; Vieillard, Louis Victorien; Rekacewicz, Claire; Parfait, Beatrice; Appay, Victor; Batteux, Frédéric; Barillot, Emmanuel; Cogné, Michel; Combadière, Béhazine; Eberhardt, Christiane S; Gorochov, Guy; Hupé, Philippe; Ninove, Laetitia; Paul, Stéphane; Pellegrin, Isabelle; van der Werf, Sylvie; Lefebvre, Maeva; Botelho-Nevers, Elisabeth; Ortega-Perez, Inmaculada; Jaspard, Marie; Sow, Samba; Lelièvre, Jean Daniel; de Lamballerie, Xavier; Kieny, Marie Paule; Tartour, Eric; Launay, Odile.
Nat Med ; 28(5): 882-884, 2022 05.
Article in English | MEDLINE | ID: covidwho-1830082

Subject(s)
COVID-19 Vaccines , COVID-19 , COVID-19/prevention & control , Humans , SARS-CoV-2 , Spike Glycoprotein, Coronavirus
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